GSTA4 anticorps (AA 29-222) (Cy3)

N° du produit ABIN7994273

Cet anticorps anti-GSTA4 Polyclonal Lapin conjugué à Cy3 (ABIN7994273) détecte spécifiquement GSTA4 dans FACS. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour GSTA4 anticorps (AA 29-222) (Cy3) (ABIN7994273)

Antigène: GSTA4 (Glutathione S-Transferase alpha 4 (GSTA4))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTA4 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-GSTA4 anticorps (Cy3)

Épitope: AA 29-222

Fonction: Anti-GSTA4 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse GSTA4 recombinant protein (Position: E29-F222).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur GSTA4

Antigène: GSTA4 (Glutathione S-Transferase alpha 4 (GSTA4))

Autre désignation: Gsta4

Sujet:

Background: Glutathione S-transferase A4, also known as GSTA4, is an enzyme which in humans is encoded by the GSTA4 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules). In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity, thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Gene Full Name: glutathione S-transferase, alpha 4

ID gène: 14860

UniProt: P24472