Grancalcin anticorps (AA 42-217) (Fluoro594)

N° du produit ABIN7995013

L’anticorps anti-Grancalcin Polyclonal Lapin est utilisé pour la détection de Grancalcin dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour Grancalcin anticorps (AA 42-217) (Fluoro594) (ABIN7995013)

Antigène: Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Grancalcin est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-Grancalcin anticorps (Fluoro594)

Épitope: AA 42-217

Fonction: Anti-Grancalcin/GCA Antibody Fluoro594 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Grancalcin/GCA recombinant protein (Position: A42-I217).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Grancalcin

Antigène: Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

Autre désignation: GCA

Sujet:

Background: Grancalcin is a protein that in humans is encoded by the GCA gene. This gene is mapped to 2q24.2. This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction, with magnesium alone, it partitions with the granule fraction, and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.

Gene Full Name: grancalcin

ID gène: 25801

UniProt: P28676