HSPB8 anticorps (AA 1-196) (Fluoro488)

N° du produit ABIN7996189

L’anticorps anti-HSPB8 Monoclonal Souris est utilisé pour la détection de HSPB8 dans des échantillons de Humain et Rat. Il a été validé pour FACS.

Aperçu rapide pour HSPB8 anticorps (AA 1-196) (Fluoro488) (ABIN7996189)

Antigène: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSPB8 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Clone: 7D8

Détail du produit anti-HSPB8 anticorps (Fluoro488)

Épitope: AA 1-196

Fonction: Anti-HSPB8/Hsp22 Antibody (monoclonal, 7D8) Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human HSPB8,Hsp22 shares 94.4%,95.4% amino acid (aa) sequence identity with mouse,rat HSPB8,Hsp22,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HSPB8/Hsp22 recombinant protein (Position: M1-T196). Human HSPB8/Hsp22 shares 94.4% and 95.4% amino acid (aa) sequence identity with mouse and rat HSPB8/Hsp22, respectively.

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HSPB8

Antigène: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Autre désignation: HSPB8

Sujet:

Background: Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Gene Full Name: heat shock protein family B (small) member 8

ID gène: 26353

UniProt: Q9UJY1