HSPA6 anticorps (C-Term) (APC)

N° du produit ABIN7996447

L’anticorps anti-HSPA6 Polyclonal Lapin est utilisé pour la détection de HSPA6 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour HSPA6 anticorps (C-Term) (APC) (ABIN7996447)

Antigène: HSPA6 (Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPA6 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-HSPA6 anticorps (APC)

Épitope: C-Term

Fonction: Anti-HSPA6 Antibody APC Conjugated

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human HSPA6, which shares 81.2% amino acid (aa) sequence identity with mouse and rat HSPA6.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HSPA6

Antigène: HSPA6 (Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))

Autre désignation: HSPA6

Sujet:

Background: Heat shock 70 kDa protein 6 is a protein that in humans is encoded by the HSPA6 gene. The HSPA6 gene, also known as heat shock 70 kDa protein 6, encodes a member of the heat shock protein 70 (HSP70) family, which functions as molecular chaperones involved in protein folding, unfolding, and transport under stress conditions. HSPA6 is induced in response to cellular stressors such as heat shock, oxidative stress, and exposure to toxic agents, where it assists in protein refolding and prevents protein aggregation, thus promoting cell survival. While HSPA6 shares significant sequence homology with other HSP70 family members, it exhibits distinct expression patterns and functional properties in different tissues and cellular contexts. Its role in various physiological processes and diseases, including neurodegenerative disorders, cancer, and cardiovascular diseases, is under investigation. Understanding the molecular mechanisms underlying HSPA6 function is crucial for elucidating its role in cellular stress responses and its potential as a therapeutic target for stress-related diseases.

Gene Full Name: heat shock protein family A (Hsp70) member 6

ID gène: 3310

UniProt: P17066