HFE anticorps (AA 82-199) (HRP)

N° du produit ABIN7996864

L’anticorps anti-HFE Polyclonal Lapin est utilisé pour la détection de HFE dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour HFE anticorps (AA 82-199) (HRP) (ABIN7996864)

Antigène: HFE (Hemochromatosis (HFE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HFE est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-HFE anticorps (HRP)

Épitope: AA 82-199

Fonction: Anti-HFE Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human HFE shares 72.2%,74.6% amino acid (aa) sequence identity with mouse,rat HFE,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HFE recombinant protein (Position: Q82-R199). Human HFE shares 72.2% and 74.6% amino acid (aa) sequence identity with mouse and rat HFE, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HFE

Antigène: HFE (Hemochromatosis (HFE))

Autre désignation: HFE

Sujet:

Background: Human hemochromatosis protein also known as the HFE protein is a protein which in humans is encoded by the HFE gene. The HFE gene is located on short arm of chromosome 6 at location 6p21.3. The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.

Gene Full Name: homeostatic iron regulator

ID gène: 3077

UniProt: Q30201

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process