Hemoglobin Alpha 1 + 2 (HBA1,HBA2) (C-Term) anticorps (APC)

N° du produit ABIN7996887

Cet anticorps Lapin Polyclonal détecte spécifiquement Hemoglobin Alpha 1 + 2 dans FACS. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Hemoglobin Alpha 1 + 2 (HBA1,HBA2) (C-Term) anticorps (APC) (ABIN7996887)

Antigène: Hemoglobin Alpha 1 + 2 (HBA1,HBA2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: APC

Application: Flow Cytometry (FACS)

Détail du produit

Épitope: C-Term

Fonction: Anti-Hemoglobin/HBA1/HBA2 Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Hemoglobin/HBA1/HBA2, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détail du antigène

Antigène: Hemoglobin Alpha 1 + 2 (HBA1,HBA2)

Autre désignation: HBA1/HBA2

Sujet:

Background: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported.

Gene Full Name: hemoglobin subunit alpha 1

ID gène: 3039, 3040

UniProt: P69905