HPSE anticorps (AA 206-457)

N° du produit ABIN7997033

Cet anticorps anti-HPSE Polyclonal Lapin (ABIN7997033) détecte spécifiquement HPSE dans WB. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour HPSE anticorps (AA 206-457) (ABIN7997033)

Antigène: HPSE (Heparanase (HPSE))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HPSE est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-HPSE anticorps

Épitope: AA 206-457

Fonction: Anti-Heparanase 1/Hpse Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Mouse Heparanase 1 shares 80.2%,96.4% amino acid (aa) sequence identity with human,rat Heparanase 1,respectively.

Attributs du produit: Anti-Heparanase 1/Hpse Antibody. Tested in WB applications. This antibody reacts with Mouse.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Heparanase 1 recombinant protein (Position: K206-K457). Mouse Heparanase 1 shares 80.2% and 96.4% amino acid (aa) sequence identity with human and rat Heparanase 1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HPSE

Antigène: HPSE (Heparanase (HPSE))

Autre désignation: Hpse

Sujet:

Background: Heparanase, also known as HPSE, is an enzyme that acts both at the cell-surface and within the extracellular matrix to degrade polymeric heparan sulfate molecules into shorter chain length oligosaccharides. Heparanase is an endo-beta-D-glucuronidase capable of cleaving heparan sulfate and has been implicated in inflammation and tumor angiogenesis and metastasis. The successful penetration of the endothelial cell layer that lines the interior surface of blood vessels is an important process in the formation of blood borne tumour metastases. Heparan sulfate proteoglycans are major constituents of this layer and it has been shown that increased metastatic potential corresponds with increased heparanase activity for a number of cell lines.

Gene Full Name: heparanase

Poids moléculaire: 65 kDa

ID gène: 15442

UniProt: Q6YGZ1

Pathways: Glycosaminoglycan Metabolic Process