HDAC11 anticorps (N-Term) (Fluoro550)

N° du produit ABIN7997731

L’anticorps anti-HDAC11 Polyclonal Lapin est utilisé pour la détection de HDAC11 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour HDAC11 anticorps (N-Term) (Fluoro550) (ABIN7997731)

Antigène: HDAC11 (Histone Deacetylase 11 (HDAC11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC11 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-HDAC11 anticorps (Fluoro550)

Épitope: N-Term

Fonction: Anti-HDAC11 Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC11, different from the related mouse sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HDAC11

Antigène: HDAC11 (Histone Deacetylase 11 (HDAC11))

Autre désignation: HDAC11

Sujet:

Background: Histone deacetylase 11 is a 39 kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. This gene encodes a class IV histone deacetylase. And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 expression is normally found in brain and testis tissue, but upregulation of HDAC11 expression has also been seen in various cancer cells. In addition, HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells. It has also been shown that inhibition of HDAC11 results in increased expression of OX40L in Hodgkin lymphoma cells.

Gene Full Name: histone deacetylase 11

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

ID gène: 79885

UniProt: Q96DB2