HTRA2 anticorps (AA 30-458) (APC)

N° du produit ABIN7998396

Cet anticorps Lapin Polyclonal détecte spécifiquement HTRA2 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour HTRA2 anticorps (AA 30-458) (APC) (ABIN7998396)

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTRA2 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-HTRA2 anticorps (APC)

Épitope: AA 30-458

Fonction: Anti-HTRA2 Antibody APC Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human HTRA2 shares 85.7% amino acid (aa) sequence identity with mouse HTRA2.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HTRA2 recombinant protein (Position: R30-E458). Human HTRA2 shares 85.7% amino acid (aa) sequence identity with mouse HTRA2.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HTRA2

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Autre désignation: HTRA2

Sujet:

Background: Serine protease HTRA2, mitochondrial is an enzyme that in humans is encoded by the HTRA2 gene. This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Gene Full Name: HtrA serine peptidase 2

ID gène: 27429

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity