HTRA2 anticorps (AA 30-458)
Aperçu rapide pour HTRA2 anticorps (AA 30-458) (ABIN7998399)
Antigène
Voir toutes HTRA2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 30-458
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Fonction
- Anti-HTRA2 Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Homologie
- Human HTRA2 shares 85.7% amino acid (aa) sequence identity with mouse HTRA2.
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Attributs du produit
- Anti-HTRA2 Antibody. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human HTRA2 recombinant protein (Position: R30-E458). Human HTRA2 shares 85.7% amino acid (aa) sequence identity with mouse HTRA2.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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Autre désignation
- HTRA2
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Sujet
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Background: Serine protease HTRA2, mitochondrial is an enzyme that in humans is encoded by the HTRA2 gene. This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Gene Full Name: HtrA serine peptidase 2
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Poids moléculaire
- 36 kDa
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ID gène
- 27429
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UniProt
- O43464
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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