HYAL3 anticorps (C-Term) (PE)

N° du produit ABIN7998562

L’anticorps anti-HYAL3 Polyclonal Lapin est utilisé pour la détection de HYAL3 dans des échantillons de Humain et Souris. Il a été validé pour FACS.

Aperçu rapide pour HYAL3 anticorps (C-Term) (PE) (ABIN7998562)

Antigène: HYAL3 (Hyaluronidase-3 (HYAL3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HYAL3 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-HYAL3 anticorps (PE)

Épitope: C-Term

Fonction: Anti-Hyaluronidase-3 HYAL3 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat sequence by three amino acids,and different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human HYAL3, different from the related rat sequence by three amino acids, and different from the related mouse sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HYAL3

Antigène: HYAL3 (Hyaluronidase-3 (HYAL3))

Autre désignation: HYAL3

Sujet:

Background: HYAL3 (hyaluronoglucosaminidase 3) is an enzyme that in humans is encoded by the HYAL3 gene, also known as LUCA3, Hyaluronidase-3, Lung carcinoma protein 3, LUCA-3, LUCA14, Minna14. By Northern blot analysis, expression of a 2.1-kb HYAL3 transcript that was strongest in testis and bone marrow, but relatively weak in other organs. HYAL3 encodes a predicted 417-amino acid protein. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.

Gene Full Name: hyaluronidase 3

Sequence Similarities: Belongs to the glycosyl hydrolase 56 family.

ID gène: 8372

UniProt: O43820

Pathways: Glycosaminoglycan Metabolic Process