HSD17B8 anticorps (AA 42-244) (Cy3)

N° du produit ABIN7998874

L’anticorps anti-HSD17B8 Polyclonal Lapin est utilisé pour la détection de HSD17B8 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour HSD17B8 anticorps (AA 42-244) (Cy3) (ABIN7998874)

Antigène: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B8 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-HSD17B8 anticorps (Cy3)

Épitope: AA 42-244

Fonction: Anti-HSD17B8 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HSD17B8 recombinant protein (Position: D42-D244).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HSD17B8

Antigène: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Autre désignation: HSD17B8

Sujet:

Background: Estradiol 17 beta-dehydrogenase 8 is an enzyme that in humans is encoded by the HSD17B8 gene. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Gene Full Name: hydroxysteroid 17-beta dehydrogenase 8

ID gène: 7923

UniProt: Q92506

Pathways: Steroid Hormone Biosynthesis