IDS anticorps (C-Term) (Fluoro550)

N° du produit ABIN7999052

Cet anticorps anti-IDS Polyclonal Lapin conjugué à Fluoro550 (ABIN7999052) détecte spécifiquement IDS dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour IDS anticorps (C-Term) (Fluoro550) (ABIN7999052)

Antigène: IDS (Iduronate 2-Sulfatase (IDS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDS est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-IDS anticorps (Fluoro550)

Épitope: C-Term

Fonction: Anti-Iduronate 2 sulfatase/IDS Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Iduronate 2 sulfatase.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IDS

Antigène: IDS (Iduronate 2-Sulfatase (IDS))

Autre désignation: IDS

Sujet:

Background: IDS (Iduronate-2-sulfatase) is a sulfatase enzyme associated with Hunter syndrome. Iduronate 2-sulfatase is involved in the lysosomal degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. Wilson et al. (1991) used an IDS cDNA clone to localize the gene to Xq28, distal to the fragile X site. Faust et al. (1992) and Daniele et al. (1993) demonstrated that the homologous Ids gene in the mouse occupies the same position on the X chromosome in relation to the FMR1, F9, and GABRA3 genes. Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase.

Gene Full Name: iduronate 2-sulfatase

Sequence Similarities: Contains 2 follistatin-like domains.

ID gène: 3423

UniProt: P22304

Pathways: Glycosaminoglycan Metabolic Process