IKZF3 anticorps (AA 162-498) (FITC)

N° du produit ABIN7999131

Cet anticorps Lapin Polyclonal détecte spécifiquement IKZF3 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IKZF3 anticorps (AA 162-498) (FITC) (ABIN7999131)

Antigène: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKZF3 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-IKZF3 anticorps (FITC)

Épitope: AA 162-498

Fonction: Anti-IKZF3 Antibody FITC Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PARP3 shares 82.2% amino acid (aa) sequence identity with mouse,rat PARP3.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PARP3 recombinant protein (Position: Q162-Q498). Human PARP3 shares 82.2% amino acid (aa) sequence identity with mouse and rat PARP3.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IKZF3

Antigène: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Autre désignation: IKZF3

Sujet:

Background: Zinc finger protein Aiolos also known as Ikaros family zinc finger protein 3 is a protein that in humans is encoded by the IKZF3 gene. This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

Gene Full Name: IKAROS family zinc finger 3

ID gène: 22806

UniProt: Q9UKT9