ING1 anticorps (Middle Region)

N° du produit ABIN7999489

L’anticorps anti-ING1 Polyclonal Lapin est utilisé pour la détection de ING1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour ING1 anticorps (Middle Region) (ABIN7999489)

Antigène: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ING1 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-ING1 anticorps

Épitope: Middle Region

Fonction: Anti-ING1 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by seven amino acids.

Attributs du produit: Anti-ING1 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human ING1, different from the related mouse sequence by seven amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ING1

Antigène: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Autre désignation: ING1

Sujet:

Background: Inhibitor of growth protein 1 is a protein that in humans is encoded by the ING1 gene. It is mapped to 13q34. This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Full Name: inhibitor of growth family member 1

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Poids moléculaire: 47 kDa

ID gène: 3621

UniProt: Q9UK53

Pathways: Protein targeting to Nucleus, Autophagy