IMPDH1 anticorps (AA 123-500) (Biotin)

N° du produit ABIN7999622

Cet anticorps anti-IMPDH1 Polyclonal Lapin conjugué à Biotin (ABIN7999622) détecte spécifiquement IMPDH1 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour IMPDH1 anticorps (AA 123-500) (Biotin) (ABIN7999622)

Antigène: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IMPDH1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-IMPDH1 anticorps (Biotin)

Épitope: AA 123-500

Fonction: Anti-IMPDH1 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human IMPDH1 recombinant protein (Position: P123-E500).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IMPDH1

Antigène: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Autre désignation: IMPDH1

Sujet:

Background: Inosine-5'-monophosphate dehydrogenase 1, also known as IMP dehydrogenase 1, is an enzyme that in humans is encoded by the IMPDH1 gene. The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: inosine monophosphate dehydrogenase 1

ID gène: 3614

UniProt: P20839

Pathways: Ribonucleoside Biosynthetic Process