ITPA anticorps (AA 1-194) (Fluoro488)

N° du produit ABIN7999635

Cet anticorps Lapin Polyclonal détecte spécifiquement ITPA dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ITPA anticorps (AA 1-194) (Fluoro488) (ABIN7999635)

Antigène: ITPA (Inosine Triphosphatase (ITPA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITPA est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-ITPA anticorps (Fluoro488)

Épitope: AA 1-194

Fonction: Anti-ITPA Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human ITPA shares 89.6%,92.1% amino acid (aa) sequence identity with mouse,rat ITPA,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ITPA recombinant protein (Position: M1-A194). Human ITPA shares 89.6% and 92.1% amino acid (aa) sequence identity with mouse and rat ITPA, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ITPA

Antigène: ITPA (Inosine Triphosphatase (ITPA))

Autre désignation: ITPA

Sujet:

Background: Inosine triphosphate pyrophosphatase is an enzyme that in humans is encoded by the ITPA gene, by the rdgB gene in bacteria E.coli and the HAM1 gene in yeast S. cerevisiae, the protein is also encoded by some RNA viruses of the Potyviridae family. This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

Gene Full Name: inosine triphosphatase

ID gène: 3704

UniProt: Q9BY32