IRF8 anticorps (C-Term)

N° du produit ABIN8001330

L’anticorps anti-IRF8 Polyclonal Lapin est utilisé pour la détection de IRF8 dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC, FACS, ICC et IF.

Aperçu rapide pour IRF8 anticorps (C-Term) (ABIN8001330)

Antigène: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Classe de qualité: Carrier-free

Détail du produit anti-IRF8 anticorps

Épitope: C-Term

Fonction: Anti-Interferon regulatory factor 8 IRF8 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse,rat sequences by two amino acids.

Attributs du produit: Anti-Interferon regulatory factor 8 IRF8 Antibody. Tested in Flow Cytometry, ICC/IF, IHC, WB applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human IRF8, different from the related mouse and rat sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur IRF8

Antigène: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Autre désignation: IRF8

Sujet:

Background: Interferon regulatory factor 8 (IRF8) also known as Interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the IRF8 gene. By genomic sequence analysis, the IRF8 gene is mapped to chromosome 16q24.1. Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the decision for a common myeloid progenitor (CMP) to differentiate into a monocyte precursor cell.

Gene Full Name: interferon regulatory factor 8

Sequence Similarities: Belongs to the IRF family.

Poids moléculaire: 48 kDa

ID gène: 3394

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin