Involucrin anticorps (C-Term) (Fluoro550)

N° du produit ABIN8003182

Cet anticorps anti-Involucrin Polyclonal Lapin conjugué à Fluoro550 (ABIN8003182) détecte spécifiquement Involucrin dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Involucrin anticorps (C-Term) (Fluoro550) (ABIN8003182)

Antigène: Involucrin (IVL)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Involucrin est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-Involucrin anticorps (Fluoro550)

Épitope: C-Term

Fonction: Anti-Involucrin/IVL Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Involucrin.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Involucrin

Antigène: Involucrin (IVL)

Autre désignation: IVL

Sujet:

Background: Involucrin?is a?protein?component of human skin and in humans is encoded by the?IVL?gene. It is a highly reactive, soluble,?transglutaminase?substrate?protein?present in?keratinocytes?of?epidermisand other?stratified squamous epithelia. It first appears in the?cell?cytosol, but ultimately becomes cross-linked to?membrane proteins?by transglutaminase thus helping in the formation of an insoluble envelope beneath theplasma membrane?functioning as a?glutamyl?donor during assembly of the cornified envelope. Additionally, Involucrin is synthesised in the?stratum spinosum?and cross linked in the?stratum granulosum?by thetransglutaminase?enzyme that makes it highly stable. Thus it provides structural support to the cell, thereby allowing the cell to resist invasion by micro-organisms.

Gene Full Name: involucrin

ID gène: 3713

UniProt: P07476