IQGAP1 anticorps (Biotin)

N° du produit ABIN8003245

Cet anticorps anti-IQGAP1 Polyclonal Lapin conjugué à Biotin (ABIN8003245) détecte spécifiquement IQGAP1 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IQGAP1 anticorps (Biotin) (ABIN8003245)

Antigène: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IQGAP1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-IQGAP1 anticorps (Biotin)

Fonction: Anti-IQGAP1 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human IQGAP1 recombinant protein (D1374-K1657).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IQGAP1

Antigène: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Autre désignation: IQGAP1

Sujet:

Background: Ras GTPase-activating-like protein IQGAP1 (IQGAP1) also known as p195 is a ubiquitously expressed protein that in humans is encoded by the IQGAP1 gene. It is mapped to 15q26.1. This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Gene Full Name: IQ motif containing GTPase activating protein 1

ID gène: 8826

UniProt: P46940

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2