IDH3B anticorps (AA 32-362) (FITC)

N° du produit ABIN8003459

Cet anticorps Lapin Polyclonal détecte spécifiquement IDH3B dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IDH3B anticorps (AA 32-362) (FITC) (ABIN8003459)

Antigène: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDH3B est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-IDH3B anticorps (FITC)

Épitope: AA 32-362

Fonction: Anti-IDH3B Antibody FITC Conjugated

Homologie: Human IDH3B shares 97% amino acid (aa) sequence identity with rat IDH3B.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human IDH3B recombinant protein (Position: A32-D362). Human IDH3B shares 97% amino acid (aa) sequence identity with rat IDH3B.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IDH3B

Antigène: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Autre désignation: IDH3B

Sujet:

Background: Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial is an enzyme that in humans is encoded by the IDH3B gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

ID gène: 3420

UniProt: O43837