KLHL12 anticorps (AA 27-331) (HRP)

N° du produit ABIN8004043

Cet anticorps anti-KLHL12 Monoclonal Souris conjugué à HRP (Clone 2G11D1) (ABIN8004043) détecte spécifiquement KLHL12 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour KLHL12 anticorps (AA 27-331) (HRP) (ABIN8004043)

Antigène: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KLHL12 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 2G11D1

Détail du produit anti-KLHL12 anticorps (HRP)

Épitope: AA 27-331

Fonction: Anti-KLHL12 Antibody (monoclonal, 2G11D1) HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human KLHL12 recombinant protein (Position: R27-I331).

Isotype: IgG2a

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur KLHL12

Antigène: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Autre désignation: KLHL12

Sujet:

Background: Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants.

Gene Full Name: kelch like family member 12

ID gène: 59349

UniProt: Q53G59