Cytokeratin 1 anticorps (AA 223-439) (HRP)

N° du produit ABIN8004087

L’anticorps anti-Cytokeratin 1 Polyclonal Lapin est utilisé pour la détection de Cytokeratin 1 dans des échantillons de Souris. Il a été validé pour IHC, WB et ELISA.

Aperçu rapide pour Cytokeratin 1 anticorps (AA 223-439) (HRP) (ABIN8004087)

Antigène: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytokeratin 1 est conjugé à/à la HRP

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Détail du produit anti-Cytokeratin 1 anticorps (HRP)

Épitope: AA 223-439

Fonction: Anti-Cytokeratin 1/Krt1 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Cytokeratin 1/Krt1 recombinant protein (Position: L223-Q439).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Cytokeratin 1

Antigène: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Autre désignation: Krt1

Sujet:

Background: Keratin 1 (KRT1), also known as Cytokeratin 1, or Keratin, type II cytoskeletal 1, is a member of the keratin family. It is specifically expressed in the spinous and granular layers of the epidermis with family member keratin 10. Mutations in this gene have been associated with the variants ofbullous congenital ichthyosiform erythroderma in which the palms and soles of the feet are affected. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. And this type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Full Name: keratin 1

ID gène: 16678

UniProt: P04104