KNG1 anticorps (Middle Region)

N° du produit ABIN8004598

Cet anticorps anti-KNG1 Polyclonal Lapin (ABIN8004598) détecte spécifiquement KNG1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour KNG1 anticorps (Middle Region) (ABIN8004598)

Antigène: KNG1 (Kininogen 1 (KNG1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KNG1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Détail du produit anti-KNG1 anticorps

Épitope: Middle Region

Fonction: Anti-Kininogen 1/KNG1 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat sequence by thirteen amino acids.

Attributs du produit: Anti-Kininogen 1/KNG1 Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of mouse Kininogen 1, different from the related rat sequence by thirteen amino acids.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse Western blot, 0.1-0.5 μg/mL, Mouse

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur KNG1

Antigène: KNG1 (Kininogen 1 (KNG1))

Autre désignation: Kng1

Sujet:

Background: Kininogen-1 (KNG1), also known as BDK or bradykinin, is a protein that in humans is encoded by the KNG1 gene. It is mapped to 3q27.3. The KNG1 gene uses alternative splicing to generate two different proteins - high - molecular - weight kininogen (HMWK) and low - molecular- weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, KNG1, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. In addition to that, KNG1 is a constituent of the blood coagulation system as well as the kinin-kallikrein system.

Gene Full Name: kininogen 1

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Poids moléculaire: 73 kDa

ID gène: 16644

UniProt: O08677

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process