KLF6 anticorps (AA 38-205) (APC)

N° du produit ABIN8004771

L’anticorps anti-KLF6 Polyclonal Lapin est utilisé pour la détection de KLF6 dans des échantillons de Humain et Rat. Il a été validé pour FACS.

Aperçu rapide pour KLF6 anticorps (AA 38-205) (APC) (ABIN8004771)

Antigène: KLF6 (Kruppel-Like Factor 6 (KLF6))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF6 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-KLF6 anticorps (APC)

Épitope: AA 38-205

Fonction: Anti-KLF6 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human KLF6 shares 92%,90% amino acid (aa) sequences identity with mouse,rat KLF6,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human KLF6 recombinant protein (Position: E38-N205). Human KLF6 shares 92% and 90% amino acid (aa) sequences identity with mouse and rat KLF6, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur KLF6

Antigène: KLF6 (Kruppel-Like Factor 6 (KLF6))

Autre désignation: KLF6

Sujet:

Background: Krueppel-like factor 6 (KLF6) is a protein that in humans is encoded by the KLF6 gene. It is a tumor suppressor gene which is located on 10p15.1. This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.

Gene Full Name: KLF transcription factor 6

Sequence Similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.

ID gène: 1316

UniProt: Q99612