Laminin anticorps (N-Term) (HRP)

N° du produit ABIN8005056

L’anticorps anti-Laminin Polyclonal Lapin est utilisé pour la détection de Laminin dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, IHC et WB.

Aperçu rapide pour Laminin anticorps (N-Term) (HRP) (ABIN8005056)

Antigène: Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Laminin est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-Laminin anticorps (HRP)

Épitope: N-Term

Fonction: Anti-Laminin 2 alpha/LAMA2 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse sequence,and different from the related rat sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Laminin 2 alpha, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Laminin

Antigène: Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))

Autre désignation: LAMA2

Sujet:

Background: Laminin, alpha-2, also known as LAMA2, is a protein that in humans is encoded by the LAMA2 gene. This gene is mapped to 6q22.33. Laminin, an extracellular protein, is a major component of the basement membrane. It is though to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

Gene Full Name: laminin subunit alpha 2

Sequence Similarities: Contains 17 laminin EGF-like domains.

ID gène: 3908

UniProt: P24043