LMOD3 anticorps (AA 45-558) (Fluoro550)

N° du produit ABIN8005305

L’anticorps anti-LMOD3 Polyclonal Lapin est utilisé pour la détection de LMOD3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour LMOD3 anticorps (AA 45-558) (Fluoro550) (ABIN8005305)

Antigène: LMOD3 (Leiomodin 3 (LMOD3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMOD3 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-LMOD3 anticorps (Fluoro550)

Épitope: AA 45-558

Fonction: Anti-LMOD3 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human LMOD3 shares 72.2% amino acid (aa) sequence identity with mouse LMOD3.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human LMOD3 recombinant protein (Position: D45-E558). Human LMOD3 shares 72.2% amino acid (aa) sequence identity with mouse LMOD3.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur LMOD3

Antigène: LMOD3 (Leiomodin 3 (LMOD3))

Autre désignation: LMOD3

Sujet:

Background: Leiomodin-3 is a protein that in humans is encoded by the LMOD3 gene. The protein encoded by this gene is a member of the leiomodin family of proteins. This protein contains three actin-binding domains, a tropomyosin domain, a leucine-rich repeat domain, and a Wiskott-Aldrich syndrome protein homology 2 domain (WH2). Localization of this protein to the pointed ends of thin filaments has been observed, and there is evidence that this protein acts as a catalyst of actin nucleation, and is important to the organization of sarcomeric thin filaments in skeletal muscles. Mutations in this gene have been associated as one cause of Nemaline myopathy, as other genes have also been linked to this disorder. Nemaline myopathy is a disorder characterized by nonprogressive generalized muscle weakness and protein inclusions (nemaline bodies) in skeletal myofibers. Patients with mutations in this gene often present with a severe congenital form of the disorder.

Gene Full Name: leiomodin 3

ID gène: 56203

UniProt: Q0VAK6