LEPREL1 anticorps (AA 106-494) (Biotin)

N° du produit ABIN8005346

Cet anticorps Lapin Polyclonal détecte spécifiquement LEPREL1 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LEPREL1 anticorps (AA 106-494) (Biotin) (ABIN8005346)

Antigène: LEPREL1 (Leprecan Like Protein 1 (LEPREL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LEPREL1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-LEPREL1 anticorps (Biotin)

Épitope: AA 106-494

Fonction: Anti-P3H2 Antibody Biotin Conjugated

Homologie: Human P3H2 shares 88.9%,89.5% amino acid (aa) sequence identity with mouse,rat P3H2,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human P3H2 recombinant protein (Position: E106-R494). Human P3H2 shares 88.9% and 89.5% amino acid (aa) sequence identity with mouse and rat P3H2, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur LEPREL1

Antigène: LEPREL1 (Leprecan Like Protein 1 (LEPREL1))

Autre désignation: P3H2

Sujet:

Background: This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: prolyl 3-hydroxylase 2

ID gène: 55214

UniProt: Q8IVL5