LRRC1 anticorps (AA 120-497) (Biotin)

N° du produit ABIN8005456

Cet anticorps anti-LRRC1 Polyclonal Lapin conjugué à Biotin (ABIN8005456) détecte spécifiquement LRRC1 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LRRC1 anticorps (AA 120-497) (Biotin) (ABIN8005456)

Antigène: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-LRRC1 anticorps (Biotin)

Épitope: AA 120-497

Fonction: Anti-LRRC1 Antibody Biotin Conjugated

Homologie: Human LRRC1 shares 91.8% amino acid (aa) sequence identity with mouse LRRC1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human LRRC1 recombinant protein (Position: L120-R497). Human LRRC1 shares 91.8% amino acid (aa) sequence identity with mouse LRRC1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur LRRC1

Antigène: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Autre désignation: LRRC1

Sujet:

Background: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.

Gene Full Name: leucine rich repeat containing 1

ID gène: 55227

UniProt: Q9BTT6