LGI4 anticorps (AA 225-531) (HRP)

N° du produit ABIN8005706

Cet anticorps Lapin Polyclonal détecte spécifiquement LGI4 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LGI4 anticorps (AA 225-531) (HRP) (ABIN8005706)

Antigène: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGI4 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-LGI4 anticorps (HRP)

Épitope: AA 225-531

Fonction: Anti-LGI4 Antibody HRP Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human LGI4 recombinant protein (Position: E225-H531).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur LGI4

Antigène: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Autre désignation: LGI4

Sujet:

Background: The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs). Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with autodominant lateral temporal epilepsy (ADTLE). However, the LGI4 gene is located in a region linked to benign familial infantile convulsions and a GC-to-AT polymorphism in LGI4 was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development.

Gene Full Name: leucine rich repeat LGI family member 4

ID gène: 163175

UniProt: Q8N135