LAIR1 anticorps (AA 142-287)
Aperçu rapide pour LAIR1 anticorps (AA 142-287) (ABIN8005919)
Antigène
Voir toutes LAIR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 142-287
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Fonction
- Anti-LAIR1 Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Attributs du produit
- Anti-LAIR1 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human LAIR1 recombinant protein (Position: Q142-H287).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
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Autre désignation
- LAIR1
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Sujet
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Background: Leukocyte-associated immunoglobulin-like receptor 1 is a protein that in humans is encoded by the LAIR1 gene. The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
Gene Full Name: leukocyte associated immunoglobulin like receptor 1
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Poids moléculaire
- 40 kDa
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ID gène
- 3903
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UniProt
- Q6GTX8
Antigène
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