LIMS1 anticorps (AA 11-172) (HRP)

N° du produit ABIN8006003

Cet anticorps Lapin Polyclonal détecte spécifiquement LIMS1 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LIMS1 anticorps (AA 11-172) (HRP) (ABIN8006003)

Antigène: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIMS1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-LIMS1 anticorps (HRP)

Épitope: AA 11-172

Fonction: Anti-LIMS1 Antibody HRP Conjugated

Homologie: Human LIMS1 shares 100% amino acid (aa) sequence identity with mouse LIMS1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human LIMS1 recombinant protein (Position: E11-A172). Human LIMS1 shares 100% amino acid (aa) sequence identity with mouse LIMS1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur LIMS1

Antigène: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Autre désignation: LIMS1

Sujet:

Background: LIM and senescent cell antigen-like-containing domain protein 1 is a protein that in humans is encoded by the LIMS1 gene. The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: LIM zinc finger domain containing 1

ID gène: 3987

UniProt: P48059