LYPD3 anticorps (AA 90-392) (Fluoro647)

N° du produit ABIN8006754

L’anticorps anti-LYPD3 Polyclonal Lapin est utilisé pour la détection de LYPD3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour LYPD3 anticorps (AA 90-392) (Fluoro647) (ABIN8006754)

Antigène: LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LYPD3 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-LYPD3 anticorps (Fluoro647)

Épitope: AA 90-392

Fonction: Anti-LYPD3 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human ILKAP shares 98%,98.7% amino acid (aa) sequence identity with mouse,rat ILKAP,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ILKAP recombinant protein (Position: E90-H392). Human ILKAP shares 98% and 98.7% amino acid (aa) sequence identity with mouse and rat ILKAP, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur LYPD3

Antigène: LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))

Autre désignation: LYPD3

Sujet:

Background: Ly6/PLAUR domain-containing protein 3 is a protein that in humans is encoded by the LYPD3 gene. Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4, and LYPD3, is a cell membrane protein that contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in the placenta, skin, and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in the esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression.

Gene Full Name: LY6/PLAUR domain containing 3

ID gène: 27076

UniProt: O95274