MAD1L1 anticorps (AA 362-632) (HRP)

N° du produit ABIN8007302

Cet anticorps Lapin Polyclonal détecte spécifiquement MAD1L1 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MAD1L1 anticorps (AA 362-632) (HRP) (ABIN8007302)

Antigène: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAD1L1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MAD1L1 anticorps (HRP)

Épitope: AA 362-632

Fonction: Anti-MAD1/MAD1L1 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human MAD1 shares 81% amino acid (aa) sequence identity with mouse MAD1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MAD1 recombinant protein (Position: L362-A632). Human MAD1 shares 81% amino acid (aa) sequence identity with mouse MAD1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MAD1L1

Antigène: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Autre désignation: MAD1L1

Sujet:

Background: Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the MAD1L1 gene. It is mapped to 7p22.3. MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 can function as a homodimer. It localizes to the centrosome during metaphase and to the spindle midzone and the midbody during anaphase and telophase. MAD1L1 may also play a role in cell cycle control and tumor suppression.

Gene Full Name: mitotic arrest deficient 1 like 1

Sequence Similarities: Belongs to the MAD1 family.

ID gène: 8379

UniProt: Q9Y6D9

Pathways: M Phase