MADD anticorps (AA 5-329) (Fluoro488)

N° du produit ABIN8007804

L’anticorps anti-MADD Polyclonal Lapin est utilisé pour la détection de MADD dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour MADD anticorps (AA 5-329) (Fluoro488) (ABIN8007804)

Antigène: MADD (MAP-Kinase Activating Death Domain (MADD))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MADD est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-MADD anticorps (Fluoro488)

Épitope: AA 5-329

Fonction: Anti-MADD Antibody Fluoro488 Conjugated

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MADD recombinant protein (Position: K5-Y329).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MADD

Antigène: MADD (MAP-Kinase Activating Death Domain (MADD))

Autre désignation: MADD

Sujet:

Background: MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the MADD gene. Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: MAP kinase activating death domain

ID gène: 8567

UniProt: Q8WXG6

Pathways: Caspase Cascade in Apoptosis