MXD1 anticorps (AA 1-221) (Fluoro550)
Aperçu rapide pour MXD1 anticorps (AA 1-221) (Fluoro550) (ABIN8008344)
Antigène
Voir toutes MXD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-221
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Fonction
- Anti-Mad/MXD1 Antibody Fluoro550 Conjugated
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived human Mad recombinant protein (Position: M1-L221).
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Isotype
- IgG
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Indications d'application
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Date de péremption
- 12 months
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- MXD1 (MAX Dimerization Protein 1 (MXD1))
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Autre désignation
- MXD1
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Sujet
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Background: MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Full Name: MAX dimerization protein 1
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ID gène
- 4084
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UniProt
- Q05195
Antigène
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