MESDC2 anticorps (AA 80-205) (Cy3)

N° du produit ABIN8009189

Cet anticorps Lapin Polyclonal détecte spécifiquement MESDC2 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MESDC2 anticorps (AA 80-205) (Cy3) (ABIN8009189)

Antigène: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MESDC2 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-MESDC2 anticorps (Cy3)

Épitope: AA 80-205

Fonction: Anti-MESDC2/MESD Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MESDC2/MESD recombinant protein (Position: D80-Q205).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MESDC2

Antigène: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Autre désignation: MESD

Sujet:

Background: Mesoderm development candidate genes 1 (MESDC1) and 2 (MESDC2) were identified from the mesoderm development (MESD) deletion interval located on mouse chromosome 7. MESD acts as a chaperone for low-density lipoprotein receptor (LDLR) proteins in the ER, and particularly associates with Wnt signaling pathway coreceptors LRP5 and LPR6. MESD is required for proper LRP5/6 folding and maturation to the cell surface, which plays a major role in Wnt signaling. The interaction between MESD and LRP5 is disrupted by a G171V mutation in LRP5 that is found in individuals with a familial phenotype characterized by high bone mass.

Gene Full Name: mesoderm development LRP chaperone

ID gène: 23184

UniProt: Q14696