MVK anticorps (AA 13-394) (Cy3)

N° du produit ABIN8009871

L’anticorps anti-MVK Polyclonal Lapin est utilisé pour la détection de MVK dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour MVK anticorps (AA 13-394) (Cy3) (ABIN8009871)

Antigène: MVK (Mevalonate Kinase (MVK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MVK est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-MVK anticorps (Cy3)

Épitope: AA 13-394

Fonction: Anti-MVK Antibody Cy3 Conjugated

Homologie: Human MVK shares 80.8%,81.4% amino acid (aa) sequence identity with mouse,rat MVK,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MVK recombinant protein (Position: K13-D394). Human MVK shares 80.8% and 81.4% amino acid (aa) sequence identity with mouse and rat MVK, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MVK

Antigène: MVK (Mevalonate Kinase (MVK))

Autre désignation: MVK

Sujet:

Background: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants.

Gene Full Name: mevalonate kinase

ID gène: 4598

UniProt: Q03426