MMS19 anticorps (AA 239-998) (Biotin)

N° du produit ABIN8011488

L’anticorps anti-MMS19 Polyclonal Lapin est utilisé pour la détection de MMS19 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour MMS19 anticorps (AA 239-998) (Biotin) (ABIN8011488)

Antigène: MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMS19 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MMS19 anticorps (Biotin)

Épitope: AA 239-998

Fonction: Anti-MMS19 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MMS19 recombinant protein (Position: E239-R998).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MMS19

Antigène: MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))

Autre désignation: MMS19

Sujet:

Background: MMS19 nucleotide excision repair protein homolog is a protein that in humans is encoded by the MMS19 gene. MMS19 (MMS19 nucleotide excision repair homolog), also known as MET18, is a 1,030 amino acid nuclear protein containing seven HEAT repeats that belongs to the MET18/MMS19 family. Via its interactions with TFIIH p80 and TFIIH p89 helicases, MMS19 plays a role in nucleotide excision repair (NER) and RNA polymerase II (Pol II) transcription. MMS19 may also function as a transcriptional coactivator of estrogen receptor. While ubiquitously expressed, highest levels of MMS19 have been found in testis. At least five distinct MMS19 protein isoforms exist, which are produced by alternative splicing events.

Gene Full Name: MMS19 cytosolic iron-sulfur assembly component

ID gène: 64210

UniProt: Q96T76

Pathways: Nuclear Hormone Receptor Binding