Monoamine Oxidase B anticorps (N-Term) (Cy3)

N° du produit ABIN8011654

Cet anticorps anti-Monoamine Oxidase B Polyclonal Lapin conjugué à Cy3 (ABIN8011654) détecte spécifiquement Monoamine Oxidase B dans FACS. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour Monoamine Oxidase B anticorps (N-Term) (Cy3) (ABIN8011654)

Antigène: Monoamine Oxidase B (MAOB)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Monoamine Oxidase B est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-Monoamine Oxidase B anticorps (Cy3)

Épitope: N-Term

Fonction: Anti-Monoamine Oxidase B/MAOB Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related rat sequence.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of mouse MAOB, identical to the related rat sequence.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Monoamine Oxidase B

Antigène: Monoamine Oxidase B (MAOB)

Autre désignation: MAOB

Sujet:

Background: MAOB (MONOAMINE OXIDASE B), also called MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.

Gene Full Name: monoamine oxidase B

Sequence Similarities: Belongs to the flavin monoamine oxidase family.

ID gène: 109731

UniProt: Q8BW75