Monoamine Oxidase B anticorps (N-Term)
Aperçu rapide pour Monoamine Oxidase B anticorps (N-Term) (ABIN8011663)
Antigène
Voir toutes Monoamine Oxidase B (MAOB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- N-Term
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Fonction
- Anti-Monoamine Oxidase B/MAOB Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- identical to the related rat sequence.
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Attributs du produit
- Anti-Monoamine Oxidase B/MAOB Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse MAOB, identical to the related rat sequence.
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Isotype
- IgG
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Indications d'application
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat Western blot, 0.1-0.5 μg/mL, Mouse, Rat
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- Monoamine Oxidase B (MAOB)
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Autre désignation
- MAOB
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Sujet
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Background: MAOB (MONOAMINE OXIDASE B), also called MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.
Gene Full Name: monoamine oxidase B
Sequence Similarities: Belongs to the flavin monoamine oxidase family.
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Poids moléculaire
- 59 kDa
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ID gène
- 109731
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UniProt
- Q8BW75
Antigène
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