MUC2 anticorps (AA 21-463) (Biotin)

N° du produit ABIN8011851

L’anticorps anti-MUC2 Polyclonal Lapin est utilisé pour la détection de MUC2 dans des échantillons de Humain. Il a été validé pour IHC, WB et ELISA.

Aperçu rapide pour MUC2 anticorps (AA 21-463) (Biotin) (ABIN8011851)

Antigène: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUC2 est conjugé à/à la Biotin

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Détail du produit anti-MUC2 anticorps (Biotin)

Épitope: AA 21-463

Fonction: Anti-MUC2 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MUC2 recombinant protein (Position: S21-D463).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MUC2

Antigène: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Autre désignation: MUC2

Sujet:

Background: Mucin 2, also known as MUC2, is a protein that in humans is encoded by the MUC2 gene. This gene encodes a member of the mucin protein family. It is mapped to 11p15.5. Mucin 2 is particularly prominent in the gut where it is secreted from goblet cells in the epithelial lining into the lumen of the large intestine. There, mucin 2, along with small amounts of related-mucin proteins, polymerizes into a gel of which 80 % by weight is oligosaccharide side-chains that are added as post-translational modifications to the mucin proteins. This gel provides an insoluble mucous barrier that serves to protect the intestinal epithelium. The primary function of the MUC2 gene product is to provide a protective barrier between the epithelial surfaces and the gut lumen. There is decreased expression of MUC2 in colonic cancer and defective polymerization of secreted mucin in ulcerative colitis.

Gene Full Name: mucin 2, oligomeric mucus/gel-forming

ID gène: 4583

UniProt: Q02817