MBNL1 anticorps (AA 89-388) (PE)

N° du produit ABIN8012156

Cet anticorps Lapin Polyclonal détecte spécifiquement MBNL1 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour MBNL1 anticorps (AA 89-388) (PE) (ABIN8012156)

Antigène: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBNL1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-MBNL1 anticorps (PE)

Épitope: AA 89-388

Fonction: Anti-MBNL1 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MBNL1 recombinant protein (Position: Q89-M388).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MBNL1

Antigène: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Autre désignation: MBNL1

Sujet:

Background: Muscleblind-like (Drosophila), also known as MBNL1, is a protein that in humans is encoded by the MBNL1 gene. It is mapped to 3q25.1-q25.2. This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.

Gene Full Name: muscleblind like splicing regulator 1

ID gène: 4154

UniProt: Q9NR56

Pathways: Ribonucleoprotein Complex Subunit Organization