Myeloperoxidase anticorps (AA 406-745) (HRP)
Aperçu rapide pour Myeloperoxidase anticorps (AA 406-745) (HRP) (ABIN8012506)
Antigène
Voir toutes Myeloperoxidase (MPO) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 406-745
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Fonction
- Anti-Myeloperoxidase/MPO Antibody HRP Conjugated
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Human Myeloperoxidase shares 90% amino acid (aa) sequence identity with mouse Myeloperoxidase.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Myeloperoxidase recombinant protein (Position:S406-S745). Human Myeloperoxidase shares 90% amino acid (aa) sequence identity with mouse Myeloperoxidase.
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Isotype
- IgG
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Indications d'application
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- Myeloperoxidase (MPO)
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Autre désignation
- MPO
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Sujet
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Background: Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function. The standard product used in this kit is the product of gene recombination, consisting of 697 (A49-S745) amino acids with the molecular mass of 80KDa.
Gene Full Name: myeloperoxidase
Sequence Similarities: Belongs to the peroxidase family. XPO subfamily.
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ID gène
- 4353
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UniProt
- P05164
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Pathways
- Chromatin Binding
Antigène
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