MIOX anticorps (AA 1-266) (Fluoro647)

N° du produit ABIN8012531

Cet anticorps Lapin Polyclonal détecte spécifiquement MIOX dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MIOX anticorps (AA 1-266) (Fluoro647) (ABIN8012531)

Antigène: MIOX (Myo-Inositol Oxygenase (MIOX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIOX est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-MIOX anticorps (Fluoro647)

Épitope: AA 1-266

Fonction: Anti-MIOX Antibody Fluoro647 Conjugated

Homologie: Human MIOX shares 89.8%,90.5% amino acid (aa) sequence identity with mouse,rat MIOX,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MIOX recombinant protein (Position: M1-K266). Human MIOX shares 89.8% and 90.5% amino acid (aa) sequence identity with mouse and rat MIOX, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MIOX

Antigène: MIOX (Myo-Inositol Oxygenase (MIOX))

Autre désignation: MIOX

Sujet:

Background: Myo-inositol oxygenase (MIOX), also known as ALDRL6, is a renal-specific member of the Aldo-keto reductase family. It catalyzes the first committed step in the Myo-inositol metabolism pathway and is widely distributed in mammalian tissues. Human Myo-inositol oxygenase shares 91 % and 96 % sequence homology with mouse and pig Myo-inositol oxygenase homologs, respectively. Myo-inositol oxygenase is responsible for the oxidative cleavage of Myo-inositol (MI) and its epimer D-chiro inositol (DCI) to D-glucuronate. The dioxygen-dependent cleavage of the C1-C6 bond in Myo-inositol is accomplished through the utilization of the FeII/FeIII binuclear iron center of MIOX. Myo-inositol oxygenase has also been implicated in complications of diabetes, including diabetic nephropathy.

Gene Full Name: myo-inositol oxygenase

ID gène: 55586

UniProt: Q9UGB7

Pathways: Inositol Metabolic Process