MYO1E anticorps (AA 221-1065) (Fluoro488)

N° du produit ABIN8012712

L’anticorps anti-MYO1E Polyclonal Lapin est utilisé pour la détection de MYO1E dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour MYO1E anticorps (AA 221-1065) (Fluoro488) (ABIN8012712)

Antigène: MYO1E (Myosin IE (MYO1E))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYO1E est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-MYO1E anticorps (Fluoro488)

Épitope: AA 221-1065

Fonction: Anti-MYO1E Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human MYO1E shares 95.9%,95.3% amino acid (aa) sequence identity with mouse,rat MYO1E,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MYO1E recombinant protein (Position: A221-Q1065). Human MYO1E shares 95.9% and 95.3% amino acid (aa) sequence identity with mouse and rat MYO1E, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MYO1E

Antigène: MYO1E (Myosin IE (MYO1E))

Autre désignation: MYO1E

Sujet:

Background: This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17.

Gene Full Name: myosin IE

ID gène: 4643

UniProt: Q12965

Pathways: Platelet-derived growth Factor Receptor Signaling