NANS anticorps (AA 1-341) (HRP)

N° du produit ABIN8013013

Cet anticorps anti-NANS Polyclonal Lapin conjugué à HRP (ABIN8013013) détecte spécifiquement NANS dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour NANS anticorps (AA 1-341) (HRP) (ABIN8013013)

Antigène: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NANS est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-NANS anticorps (HRP)

Épitope: AA 1-341

Fonction: Anti-NANS Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human NANS shares 96.2% amino acid (aa) sequence identity with mouse NANS.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NANS recombinant protein (Position: M1-E341). Human NANS shares 96.2% amino acid (aa) sequence identity with mouse NANS.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NANS

Antigène: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Autre désignation: NANS

Sujet:

Background: Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene. This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

Gene Full Name: N-acetylneuraminate synthase

ID gène: 54187

UniProt: Q9NR45