NANS anticorps (AA 1-341) (APC)

N° du produit ABIN8013014

Cet anticorps Lapin Polyclonal détecte spécifiquement NANS dans FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour NANS anticorps (AA 1-341) (APC) (ABIN8013014)

Antigène: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NANS est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-NANS anticorps (APC)

Épitope: AA 1-341

Fonction: Anti-NANS Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human NANS shares 96.2% amino acid (aa) sequence identity with mouse NANS.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NANS recombinant protein (Position: M1-E341). Human NANS shares 96.2% amino acid (aa) sequence identity with mouse NANS.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NANS

Antigène: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Autre désignation: NANS

Sujet:

Background: Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene. This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

Gene Full Name: N-acetylneuraminate synthase

ID gène: 54187

UniProt: Q9NR45