NQO1 anticorps (C-Term) (FITC)

N° du produit ABIN8013376

Cet anticorps anti-NQO1 Polyclonal Lapin conjugué à FITC (ABIN8013376) détecte spécifiquement NQO1 dans FACS. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour NQO1 anticorps (C-Term) (FITC) (ABIN8013376)

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NQO1 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-NQO1 anticorps (FITC)

Épitope: C-Term

Fonction: Anti-NQO1 Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse,rat sequences by five amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human NQO1, different from the related mouse and rat sequences by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NQO1

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Autre désignation: NQO1

Sujet:

Background: This gene is a member of the NAD (P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. And this FAD-binding protein forms homodimers and reduces quinones to hydroquinones. In addition, this protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Full Name: NAD(P)H quinone dehydrogenase 1

Sequence Similarities: Belongs to the NAD (P)H dehydrogenase (quinone) family.

ID gène: 1728

UniProt: P15559