NQO1 anticorps (AA 1-274) (FITC)

N° du produit ABIN8013387

L’anticorps anti-NQO1 Polyclonal Lapin est utilisé pour la détection de NQO1 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour NQO1 anticorps (AA 1-274) (FITC) (ABIN8013387)

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NQO1 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-NQO1 anticorps (FITC)

Épitope: AA 1-274

Fonction: Anti-NQO1 Antibody FITC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NQO1 recombinant protein (Position: M1-K274).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NQO1

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Autre désignation: NQO1

Sujet:

Background: NAD(P)H dehydrogenase [quinone] 1 is an enzyme that in humans is encoded by the NQO1 gene. This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. And this FAD-binding protein forms homodimers and reduces quinones to hydroquinones. In addition, this protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Full Name: NAD(P)H quinone dehydrogenase 1

ID gène: 1728

UniProt: P15559